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Thorsten Will


email: thorsten.will[at]
Telephone: +49 681 302 70713
Postal address: Center for Bioinformatics
Gebäude E2 1, R. 302
P.O. Box 15 11 50
D-66041 Saarbrücken


Thorsten Will

curriculum vitae

B.Sc. in Computational Biology at Saarland University, Saarbrücken, Germany (2011)
M.Sc. in Bioinformatics at Saarland University, Saarbrücken, Germany (2014)
PhD student, Center for Bioinformatics, Saarland University (since 2014)

research areas

  • transcriptional regulation
  • protein-protein interaction networks
  • data integration


Nazarieh, M., Wiese, A., Will, T., Hamed, M.,Helms, V. (2016). BMC System Biology. Identification of key player genes in gene regulatory networks.

Will, T. and Helms, V. (2015). Bioinformatics. PPIXpress: construction of condition-specific protein interaction networks based on transcript expression.

Will, T. (2014). Predicting Transcription Factor Complexes: A Novel Approach to Data Integration in Systems Biology. Springer. ISBN 3658082682.

Will, T. and Helms, V. (2014). Bioinformatics, Vol. 30 ECCB 2014, p- i415-i421. Identifying transcription factor complexes and their roles.

Will, T., Hutter, M., Jauch, J., and Helms, V. (2013). J. Comp. Chem., Vol. 34, p. 2485-2492. Batch tautomer generation with MolTPC.


The rewiring of the proteome during blood development (poster). Cell Physics, Saarbrücken (2016)

Identifying regulatory protein complexes from domain-level protein interaction networks (oral). 6th Bioinformatics and Stem Cells Satellite Workshop, Bonn (2015)

Batch tautomer generation and more with MolTPC (poster). 29th Molecular Modelling Workshop, Erlangen (2015)

Identifying transcription factor complexes and their roles (poster). Cell Physics, Saarbrücken (2014)

Identifying transcription factor complexes and their roles (oral). 13th European Conference on Computational Biology, Strasbourg (2014)

Finding Low Energy Conformations in a Haystack of Tautomers (oral). Computer Simulation and Theory of Macromolecules, Hünfeld (2012)


PPICompare - detection of rewiring events in protein interaction networks

MCDS Cytoscape App - approximation of minimum connected dominating set (together with Maryam)

PPIXpress - specific protein interaction networks from transcript expression

DACO - domain-aware cohesiveness optimization algorithm

MolTPC - fully automatic tautomer generation and more


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