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Studying Bioinformatics in Saarbrücken
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Spezialvorlesung Bioinformatik:
Membrane Bioinformatics

Summer Semester 2006


Lecturers: Prof. Dr. Volkhard Helms, Dr. Rainer Böckmann

Lecture: Thursday, 9:00 am - 11:00 am, building E1 3, R. 0.16

Tutorial 1: May 11, 4:00 pm - 6:00 pm, building E1 1, seminar room UG (basement)

Requirements: Bioinformatics I and II

Condition for certification: Oral exam

Leistungspunkte/Credits: 5 (V2/Ü 1)

This course is taught in English language.

Topics to be covered:

  1. Introduction
  2. Physico-chemical Properties of Membranes
  3. Electrostatics (KCSA-Channel), MD-Simulation of Membrane Proteins
  4. Membrane: Peptide Mellittin - antibacterial Peptides
  5. Electroporation and Fusion
  6. Prediction of Function/Classification of GPCRs
  7. Predicting TM-Regions → Hidden Markov Models
  8. Structural Modeling of Membrane Proteins
  9. Predicting Topology of Membrane Proteins → G. von Heijne
  10. Absorption of Peptides and Proteins on Membranes

Lectures of Dr. Böckmann
Lectures of Prof. Helms:
6th Lecture: June 8 ppt pdf Suggested Reading
7th Lecture: June 22 ppt pdf
8th Lecture: June 29 ppt pdf Assignment 3 + 4
HINT
9th Lecture: July 6 ppt pdf
10th Lecture: July 13 ppt pdf Suggested Reading
11th Lecture: July 20