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You are here: Home Teaching Previous semesters WS 2009/10 Special-topic Lecture Bioinformatics: Modern Methods in Drug Discovery

Spezialvorlesung: Modern Methods in Drug Discovery WS 09/10

General Information

Lecturer: Dr. Michael Hutter

Tutor: Dr. Michael Hutter

Lecture: Monday, 10:15 am - 11:45 am, building E 1 3, R 0.15
Tutorial: Wednesday, 10:15 am - 11:45 am, CIP Pool Bioinformatik, room 104, every second week

Information: This course can be used as a "Spezialvorlesung der Bioinformatik/Special-topic Lecture Bioinformatics"

Note: This course will be presented in English, the final exam will be available in German too.

Requirements:

  • basic knowledge of Organic Chemistry and Genetics
  • scope of the lectures:
    Bioinformatik I + II
    Computational Chemistry
    Softwarewerkzeuge der Bioinformatik

The questionnaire gives you an idea about the required knowledge.
Due to the limited capacity of the room, the number of participants
will be limited to about 20.


Registration: via E-mail starting October by name and Matrikelnr.
to:  Kerstin Gronow-Pudelek


Students that have successfully passed the following courses
will be considered in the first place:
Bioinformatik I
Bioinformatik II
Computational Chemistry I
Softwarewerkzeuge der Bioinformatik


Master course students with a bachelor degree from another university can also take part if successful participation of equivalent courses has been proved.

 

Scope: The focus of this course is the computer based prediction of suitable pharmaceutical drugs and the search for new potential targets in the human genome. Following topics are covered:

  • molecular origin of typical diseases and the mode of action of drugs
  • virtual substance libraries and query strategies
  • in silico eADMET models and filters, bioavailability
  • statistics and QSAR methods
  • metabolism, toxicology and adverse side effects, also considering biomarkers
  • polymorphism and susceptible genes
  • identification of orthologous genes to derive new targets and model organisms
  • current trends and strategies of drug design


Schein/Certification: Grade of certification ("Schein") is based on the final exam only.

Condition for participation in the final exam: At least 50% of the points of the assignments.

Date of the exam: January 25th, 2010, 10:15 am. Builidng E2.1 (next to Library) Room 0.07 (ground floor).

RESULTS of the examination of Monday, January 25

 

Leistungspunkte/Credits: 5 (2 V + 1 Ü)

This course is taught in English.

Lectures:

1st Lecture, October 19 pdf
pps
Assignment

2nd Lecture, October 26  pdf
pps

Tutorial 1: October 28 
3rd Lecture, November 2 pdf
pps

Tutorial 2: November 4
no Lecture on November 9




4th Lecture November 16
pdf
pps

Tutorial 3: November 18
5th Lecture, November 23
pdf
pps


6th Lecture, November 30
pdf
pps

Tutorial 4: December 2
7th Lecture, December 7
pdf
pps


8th Lecture, December 14
pdf
pps

Tutorial 5: December 16
9th Lecture, January 4
pdf
pps

Total amounts assignments 1-5

10th Lecture, January 11
pdf
pps


Tutorial 6: January 13
11th Lecture, January 18
pdf
pps


12th Lecture, January 20
pdf
pps

Building E2.1 Room 0.07 (ground floor)

Exam, January 25



Building E2.1 Room 0.07 (ground floor)

13th Lecture, February 1



Building E2.1 Room 0.07 (ground floor)

 

 

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